Position title: Professor
Phone: (608) 263-9906
Ph.D. in Pharmacology, University of Washington-Seattle
The research in our laboratory focuses on understanding the molecular mechanisms that regulate neural stem cells and neuronal development, with the goal of developing better treatment for neurodevelopmental and neurological disorders. We use transgenic mice, neural stem cells (NSC), human pluripotent stem cells (iPSC, ESC), and CRISPR gene-edited stem cells as model systems. We employ cutting edge genetic, genomic, proteomic, imaging, and behavioral methods to interrogate the roles of genes, epigenetic regulators, RNAs, and proteins in neuronal development. We determine how the mutations of these regulators may contribute to brain disorders and identify potential therapeutic targets and treatment methods.
Stem cells, neural development, RNA, gene, autism