Position title: Assistant Professor, Departments of Radiology, Psychiatry, and Biomedical Engineering


Phone: (608) 265-4792

John Paul Yu headshot


Radiology, Division of Neuroradiology
Biomedical Engineering


Ph.D. in Biophysics and Computational Biology, University of Illinois, Urbana-Champaign, Urbana, IL, USA
M.D., University of Illinois, Urbana-Champaign, Urbana, IL, USA
Residency in Diagnostic Radiology, University of California, San Francisco, CA, USA
Fellowship in Diagnostic Neuroradiology, University of California, San Francisco, CA, USA

Research Description:

I lead a systems neuroimaging laboratory that is currently aligned three major thematic and interrelated areas of interest:

  1. Examining the impact of genes, the environment, and geneenvironment interactions on quantitative brain microstructure in neurocognitive and neuropsychiatric illness.
  2. Biological validation and clinical translation of methodological innovations in diffusion weighted MRI for accurate diagnosis and tracking therapeutic outcomes in patient care, clinical trials, and patientoriented research.
  3. Development of PET neuroimaging methods for the sensitive detection and characterization of synaptic density and synaptic loss in neurologic and psychiatric illness.

At the heart of my collaborative and transdisciplinary research program is a desire to advance our understanding of the biological correlates underpinning measures of advanced quantitative diffusion weighted imaging and to leverage these insights to understand the biological transformations taking place that drive the progression from healthy cognition to cognitive dysfunction and neuropsychiatric illness.

Research Key Words:

Neuropsychiatric Illnesses, MRI Diagnosis, PET Neuroimaging, Cognitive Dysfunction

Link to Lab Website

Link to Publications