Position title: Assistant Professor, Department of Pathology and Laboratory Medicine
M.S. in Immunology, University of Iowa, Iowa City, IA, USA
Ph.D. in Molecular and Cellular Biology, University of Iowa, Iowa City, IA, USA
Postdoctoral in Pathology and Immunology, Washington University School of Medicine, St. Louis, MO,USA
My research at the University of Wisconsin utilizes cellular, biochemical, molecular, and in vivo models to explore the role of metabolism and metabolites in modifying the microglial response in AD pathology. My lab is a strong interdisciplinary environment that integrates both immunopathological and neuropathological research to interrogate questions regarding the innate immune response in neurodegeneration. My team of trainees and professional specialists are working to further understand how metabolic and transcriptional changes in microglia induced by systemic inflammation influence the microglial response during AD pathogenesis, exploring how metabolic changes brought about by AD pathology can shape the innate immune response to AD, examining the impact of host microbiota and microbiota–derived metabolites on microglial function in AD, and working towards the development of novel therapeutic strategies aimed at modulating microglial responses in AD.
Research Key Words:
Neurodegenerative Disease, AD Pathology, Neuroinflammation, Microglia Modulation