Position title: Professor, Department of Comparative Biosciences
Phone: (608) 262-4264
D.V.M. in Veterinary Medicine, The Ministry of Agriculture and Fishery, Japan
Ph.D. in Veterinary Medicine, University of Tokyo, Tokyo, Japan
My laboratory engages in basic and translational studies using human stem cells to develop therapeutic strategies for neuromuscular and musculoskeletal diseases. Through these studies, I have shown that using stem cells to deliver growth factors directly into the skeletal muscle (i.e. nerve terminals of motor neurons) could restore motor function in a rat model of familial amyotrophic lateral sclerosis (ALS).
My current research directions also include in vitro modeling and tissue engineering to study musculoskeletal biology and diseases by using two–dimensional (2D) and three–dimensional (3D) culture platforms. This research focuses on developing stem cell technology for use in treating and modeling human development and pathology. Specifically, we have engaged in basic and translational studies using human neural progenitor cells, mesenchymal stem cells, and pluripotent stem cells to develop therapeutic strategies for neuromuscular and musculoskeletal diseases.
Research Key Words:
Stem Cell Technology, Therapeutic Applications, Neuromuscular and Musculoskeletal Diseases