Jayshree Samanta

Position title: Assistant Professor

Email: jsamanta@wisc.edu

Phone: (608) 262-4686

Department:

Comparative Biosciences

Education:

Ph.D. in Neuroscience, Northwestern University

MBBS in Medicine and Surgery, Grant Medical College

Research Description:

The Samanta lab focuses on how neural stem cells generate myelin in the brain during development as well as during recovery from a demyelinating insult i.e. remyelination. The myelin sheath is a specialized membrane synthesized by oligodendrocytes that wraps around the nerves in the brain. Understanding the origin of myelinating cells and the signals which trigger their activation, migration and differentiation has major therapeutic implications for myelin disorders. We are examining these processes using mouse models of myelin diseases in vivo and tissue culture of adult neural stem cells in vitro.

Key Words:

Oligodendrocyte, neural stem cell, neurodegenerative disease, myelin

Link to Lab Website

Link to Publications