Advisor: Luigi Puglielli
I am interested in the molecular mechanisms of neurological disease states. I am investigating the metabolomics of the neuron; specifically the quality control system that cells have in place to check for properly folded proteins. The implications for my research include Alzheimer’s Disease, Autism Spectrum Disorder, and Spastic Paraplegia, to name a few.
I use an array of biochemical and molecular techniques to study intracellular communication with regards to the Endoplasmic Reticulum quality control system. When this system is out of balance, the implications are impressive, providing an amazingly interwoven molecular system to research.