University of Wisconsin–Madison

Neuronal Circuits

This research area is concerned with how cells behave when connected together to form neural networks, and thus forms the link between molecular and systems neuroscience. We are now poised to explain how the activity of groups of cells in the brain contributes to specific behaviors, and how patterns of activity in groups of cells arise based on the properties of individual cells in the network. Nonlinear interactions between voltage and ligand-gated channels, second messenger systems, exocytosis, and other processes dictates that these networks will not just be the sums of their parts, but will produce unexpected and complex patterns of activity. Faculty address these questions in a diverse array of systems. For example, researchers investigate how sensory stimuli are extracted in the periphery, processed in parallel, and reunited centrally to form cohesive percepts, and how this information is used to plan and execute motor output. Faculty are also investigating how cortical circuits are reorganized during learning, how memories are stored and retrieved, and what goes wrong with these processes in pathologies such as epilepsy and Parkinson’s diseases. Others study the pattern generating circuitry controlling locomotion and breathing. The circuit-based mechanisms underlying stress responses, waking and arousal, and neuroendocrine regulation of the cardiovascular system are also being addressed. Students have the opportunity to learn state-of-the art techniques for monitoring activity and assaying connectivity within neural networks, including simultaneous patch clamp recordings from visually identified cell pairs and triplets, single and multiple cell staining, imaging with voltage and calcium-sensitive fluorescent dyes, electrophysiological recordings, in vivo, and neural network modeling.

Vaishali P. Bakshi

Associate Professor, Department of Psychiatry

(608) 265-6062

Matthew I. Banks

Associate Professor, Department of Anesthesiology

(608) 261-1143

Craig W. Berridge

Professor, Department of Psychology

(608) 265-5938

Mark S. Brownfield

Associate Professor, Department of Comparative Biosciences, School of Veterinary Medicine

(608) 263-5863

Michael Cahill

Assistant Professor, Department of Comparative Biosciences

Miles Epstein

Professor Emeritus

(608) 263-5074

Stephen C. Gammie

Professor, Department of Integrative Biology

(608) 262-3457

Xin Huang

Associate Professor, Department of Neuroscience

(608) 265-2744

Meyer B. Jackson

Professor, Department of Neuroscience

(608) 262-9111

Stephen M. Johnson

Associate Professor, Department of Comparative Biosciences, School of Veterinary Medicine

(608) 263-2996

Mathew V. Jones

Associate Professor, Department of Neuroscience

(608) 263-4394

Lingjun Li

Professor, Department of Pharmacy

(608) 265-8491

Xuelin Lou

Assistant Professor, Department of Neuroscience

(608) 263-6265

Donata Oertel

Professor, Department of Neuroscience

(608) 263-6281

Robert A. Pearce

Chair and Professor, Department of Anesthesiology

(608) 263-0208

Luis Populin

Associate Professor, Department of Neuroscience

(608) 265-6451

Bas Rokers

Associate Professor, Department of Psychology

(608) 262-8992

Ari Rosenberg

Assistant Professor, Department of Neuroscience

(608) 265-5782

Paul A. Rutecki

Professor and Vice Chairperson, Department of Neurology; Director of VA Northwest Epilepsy Center of Excellence

(608) 263-5448

Yuri Saalmann

Assistant Professor, Department of Psychology

(608) 262-8671

Philip H. Smith

Professor, Department of Neuroscience

(608) 262-0291

Anthony O. W. Stretton

Professor, Department of Integrative Biology

(608) 262-2172

Ei Terasawa

Professor, Department of Pediatrics

(608) 263-3579

Robert G. Thorne

Assistant Professor, School of Pharmacy

(608) 890-3508

Giulio Tononi

Professor, Department of Psychiatry

(608) 263-6063

Daniel J. Uhlrich

Professor, Department of Neuroscience; Associate Vice Chancellor for Research Policy, UW Graduate School

(608) 262-1044

Marc Wolman

Assistant Professor, Department of Integrative Biology

(608) 890-1962

Jay Yang

Professor, Department of Anesthesiology

(608) 265-6710

Lea Ziskind-Conhaim

Professor, Department of Neuroscience

(608) 263-3382