University of Wisconsin–Madison

Membrane Excitability and Synaptic Transmission

The nervous system uses electrical signals to encode and process information. These signals take the form of action potentials within neurons and synaptic potentials between neurons. The molecules responsible for these signals include voltage-gated channels, which generate and shape action potentials; neurotransmitter receptors, which generate and shape synaptic potentials; and membrane trafficking proteins, which catalyze the fusion of neurotransmitter-containing vesicles with the plasma membrane. Research into membrane excitability and synaptic transmission provides insight into the cellular and molecular basis for learning and memory, and illuminates the molecular mechanisms of neurological disease and drug action. Faculty in the Neuroscience Training Program investigate these questions in a wide variety of models from yeast and Drosophila to humans, using a broad range of techniques including patch clamping, electrophysiology, and cellular imaging.

 

Tracy L. Baker

Associate Professor, Department of Comparative Biosciences

bakert@vetmed.wisc.edu

(608) 890-2964

Matthew I. Banks

Associate Professor, Department of Anesthesiology

mibanks@wisc.edu

(608) 261-1143

Michael Cahill

Assistant Professor, Department of Comparative Biosciences

michael.cahill@wisc.edu

Baron Chanda

Associate Professor, Department of Neuroscience

chanda@wisc.edu

(608) 265-3936

Edwin R. Chapman

Professor, Department of Neuroscience; Investigator, Howard Hughes Medical Institute

chapman@wisc.edu

(608) 263-1762

Cynthia Czajkowski

Professor, Department of Neuroscience

cmczajko@wisc.edu

(608) 265-5863

Meyer B. Jackson

Professor, Department of Neuroscience

mbjackso@wisc.edu

(608) 262-9111

Mathew V. Jones

Associate Professor, Department of Neuroscience

mathewjones@wisc.edu

(608) 263-4394

Xuelin Lou

Assistant Professor, Department of Neuroscience

xluo3@wisc.edu

(608) 263-6265

Donata Oertel

Professor, Department of Neuroscience

doertel@wisc.edu

(608) 263-6281

Robert A. Pearce

Chair and Professor, Department of Anesthesiology

rapearce@wisc.edu

(608) 263-0208

Gail A. Robertson

Professor, Department of Neuroscience

garobert@wisc.edu

(608) 265-3339

Subhojit Roy

Professor, Department of Neuroscience and Pathology

roy27@wisc.edu

(608) 263-1227

Arnold E. Ruoho

Professor, Department of Neuroscience

aeruoho@wisc.edu

(608) 263-5382

Paul A. Rutecki

Professor and Vice Chairperson, Department of Neurology; Director of VA Northwest Epilepsy Center of Excellence

rutecki@neurology.wisc.edu

(608) 263-5448

Anthony O. W. Stretton

Professor, Department of Integrative Biology

aostrett@wisc.edu

(608) 262-2172

Lea Ziskind-Conhaim

Professor, Department of Neuroscience

lziskind@wisc.edu

(608) 263-3382