Korri Burnett

Korri Burnett
Title
Ph.D. Candidate
E-mail
khburnett@wisc.edu

Advisor:

Rotating

Research Description:

During my lab rotation with Xinyu Zhao, I worked on optimizing an immunohistochemistry protocol. Ultimately, we wanted to more fully understand how the methyl-binding protein MBD1 regulates neural stem cell differentiation and neurogenesis in the dentate gyrus of the adult mouse brain. I wanted to localize MBD1, the netrin-1 receptor/tumor suppressor DCC, and a protein that is a part of a chromatin remodeling complex, BAF170. I used different types of antibodies, manipulated concentrations of reagents, and used antigen retrieval protocols to optimize staining. I am now rotating with Darcie Moore, who focuses on identifying the mechanisms that neural stems cells use to create the asymmetric segregation of cargoes.